Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 5/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 2/20 | 0.55 |
| ▸ | EIF4A3 | P38919 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | ALPL | P05186 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.49 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.49 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.49 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | DAO | P14920 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20494459 | 1.00 | FLT3 (0.55) | FLT3PDGFRBPDGFRAEIF4A3MEN1 | |
| SCHEMBL4263996 | 0.88 | PDGFRB (0.61) | FLT3PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL335655 | 0.88 | FLT3 (0.68) | FLT3PDGFRBPDGFRAEIF4A3MEN1 | |
| SCHEMBL30189510 | 0.88 | FLT3 (0.68) | FLT3PDGFRBPDGFRAEIF4A3MEN1 | |
| SCHEMBL30071254 | 0.87 | NPC1 (0.55) | FLT3PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL20495078 | 0.87 | NPC1 (0.55) | FLT3PDGFRBPDGFRAMEN1KMT2A | |
| SCHEMBL7222628 | 0.83 | PIN1 (0.61) | FLT3PDGFRBPDGFRAEIF4A3ALPL | |
| SCHEMBL3389181 | 0.83 | HSD17B10 (0.66) | FLT3EIF4A3MEN1KMT2AKDM4E | |
| SCHEMBL20494223 | 0.81 | SMAD3 (0.60) | FLT3PDGFRBEIF4A3ALPLKDM4E | |
| SCHEMBL30071340 | 0.81 | SMAD3 (0.60) | FLT3PDGFRBEIF4A3ALPLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770224-B | Indole derivatives as efflux pump inhibitors | 罗格斯新泽西州立大学 | 2022-11-18 | — | — | CN | disclosed |