Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 12/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25496276 | 1.00 | ABCG2 (0.42) | ABCG2ABCB1EGFRKDM4EHTR2A | |
| SCHEMBL24894488 | 0.95 | ABCG2 (0.40) | ABCG2ABCB1EGFRKDM4EHTR2A | |
| SCHEMBL25978339 | 0.85 | ACHE (0.40) | KDM4EFFAR1 | |
| SCHEMBL25496279 | 0.84 | ABCG2 (0.41) | ABCG2ABCB1EGFRKDM4EFFAR1 | |
| SCHEMBL30074393 | 0.84 | ABCG2 (0.41) | ABCG2ABCB1EGFRKDM4EFFAR1 | |
| SCHEMBL25496277 | 0.84 | ABCG2 (0.47) | ABCG2ABCB1KDM4EFFAR1 | |
| SCHEMBL30074414 | 0.84 | ABCG2 (0.47) | ABCG2ABCB1KDM4EFFAR1 | |
| SCHEMBL29197617 | 0.82 | ABCG2 (0.37) | ABCG2ABCB1EGFRKDM4EHTR2A | |
| SCHEMBL25345611 | 0.81 | CRBN (0.32) | ABCG2CRBN | |
| SCHEMBL18750482 | 0.81 | CRBN (0.32) | ABCG2CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4087584-A2 | CELL SURFACE RECEPTOR BINDING COMPOUNDS AND CONJUGATES | Lycia Therapeutics, Inc. (US) | 2022-11-16 | — | — | EP | disclosed |