Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.61 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.61 |
| ▸ | NMUR2 | Q9GZQ4 | 5/20 | 0.59 |
| ▸ | NMUR1 | Q9HB89 | 5/20 | 0.59 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.58 |
| ▸ | RAMP3 | O60896 | 1/20 | 0.55 |
| ▸ | CALCR | P30988 | 1/20 | 0.55 |
| ▸ | KDM1A | O60341 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 1/20 | 0.54 |
| ▸ | KDM5A | P29375 | 1/20 | 0.54 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.54 |
| ▸ | EP300 | Q09472 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | CXCR4 | P61073 | 2/20 | 0.53 |
| ▸ | TFPI | P10646 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30302482 | 0.89 | NMUR2 (0.62) | OPRM1OPRD1NMUR2NMUR1EPHA2 | |
| SCHEMBL30974354 | 0.88 | OPRM1 (0.58) | OPRM1OPRD1NMUR2NMUR1EPHA2 | |
| SCHEMBL29865083 | 0.88 | OPRM1 (0.62) | OPRM1OPRD1NMUR2NMUR1EPHA2 | |
| SCHEMBL29865041 | 0.88 | OPRM1 (0.62) | OPRM1OPRD1NMUR2NMUR1EPHA2 | |
| SCHEMBL29864847 | 0.88 | OPRM1 (0.62) | OPRM1OPRD1NMUR2NMUR1EPHA2 | |
| SCHEMBL29860140 | 0.88 | RAMP3 (0.60) | OPRM1OPRD1NMUR2NMUR1EPHA2 | |
| SCHEMBL30844077 | 0.87 | OPRD1 (0.66) | OPRM1OPRD1NMUR2NMUR1EPHA2 | |
| SCHEMBL32671608 | 0.87 | RAMP3 (0.60) | OPRM1OPRD1NMUR2NMUR1EPHA2 | |
| SCHEMBL31174223 | 0.87 | NPY2R (0.64) | RAMP3CALCRKDM1AMAOBKDM5A | |
| SCHEMBL29864806 | 0.86 | OPRM1 (0.59) | OPRM1OPRD1NMUR2NMUR1EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230093708-A1 | PROTEIN NANOPARTICLE DESIGN AND APPLICATION | DUKE UNIVERSITY | 2023-03-23 | — | — | US | disclosed |
| EP-4087616-A1 | PROTEIN NANOPARTICLE DESIGN AND APPLICATION | Duke University (US) | 2022-11-16 | — | — | EP | disclosed |