Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | CTSG | P08311 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.31 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3859771 | 1.00 | ALDH1A1 (0.35) | ALDH1A1NPSR1MAPK1MEN1KMT2A | |
| SCHEMBL14312232 | 1.00 | ALDH1A1 (0.35) | ALDH1A1NPSR1MAPK1MEN1KMT2A | |
| SCHEMBL14312248 | 0.91 | ALDH1A1 (0.37) | ALDH1A1NPSR1MAPK1MEN1KMT2A | |
| SCHEMBL1412659 | 0.91 | ALDH1A1 (0.37) | ALDH1A1NPSR1MAPK1MEN1KMT2A | |
| SCHEMBL14312213 | 0.91 | ALDH1A1 (0.37) | ALDH1A1NPSR1MAPK1MEN1KMT2A | |
| SCHEMBL1412751 | 0.87 | ALDH1A1 (0.35) | ALDH1A1NPSR1MAPK1MEN1KMT2A | |
| SCHEMBL15030970 | 0.85 | ALDH1A1 (0.37) | ALDH1A1NPSR1MAPK1MEN1KMT2A | |
| SCHEMBL11180056 | 0.85 | ALDH1A1 (0.38) | ALDH1A1KDM4ESLC22A1LMNA | |
| SCHEMBL9639997 | 0.85 | EPHX2 (0.35) | ALDH1A1MAPK1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL15102759 | 0.84 | ALDH1A1 (0.33) | ALDH1A1NPSR1MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12258593-B2 | Hydrolase and method for producing (1S,2S)-1-alkoxycarbonyl-2-vinylcyclopropane carboxylic acid using same | UBE CORPORATION (JP) | 2025-03-25 | — | — | US | disclosed |
| CN-111918969-B | Novel hydrolase and process for producing (1S, 2S) -1-alkoxycarbonyl-2-vinylcyclopropanecarboxylic acid using the same | 株式会社API | 2024-11-19 | — | — | CN | disclosed |
| US-20230323317-A1 | NOVEL HYDROLASE AND METHOD FOR PRODUCING (1S,2S)-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE CARBOXYLIC ACID USING SAME | API CORPORATION (JP) | 2023-10-12 | — | — | US | disclosed |
| CN-111918969-A | Novel hydrolase and process for producing (1S,2S) -1-alkoxycarbonyl-2-vinylcyclopropanecarboxylic acid using the same | 株式会社API | 2020-11-10 | — | — | CN | disclosed |
| EP-2537825-B1 | METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE | API CORP (JP) | 2016-09-14 | — | — | EP | disclosed |
| EP-2612913-B1 | NOVEL HYDROLASE PROTEIN | API CORP (JP) | 2016-07-27 | — | — | EP | disclosed |
| EP-2612913-B1 | NOVEL HYDROLASE PROTEIN | API CORP (JP) | 2016-07-27 | — | — | EP | disclosed |
| US-9334509-B2 | Hydrolase protein | API CORPORATION (JP) | 2016-05-10 | — | — | US | disclosed |
| US-9334509-B2 | Hydrolase protein | API CORPORATION (JP) | 2016-05-10 | — | — | US | disclosed |
| US-9334509-B2 | Hydrolase protein | API CORPORATION (JP) | 2016-05-10 | — | — | US | disclosed |
| US-20130224812-A1 | Process for Resolving Cyclopropyl Diesters | BRISTOL-MYERS SQUIBB COMPANY (US) | 2013-08-29 | — | — | US | disclosed |
| EP-2612913-A1 | NOVEL HYDROLASE PROTEIN | API Corporation (JP) | 2013-07-10 | — | — | EP | disclosed |
| EP-2612913-A1 | NOVEL HYDROLASE PROTEIN | API Corporation (JP) | 2013-07-10 | — | — | EP | disclosed |
| US-20130130338-A1 | NOVEL HYDROLASE PROTEIN | API CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130130338-A1 | NOVEL HYDROLASE PROTEIN | API CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130130338-A1 | NOVEL HYDROLASE PROTEIN | API CORPORATION (JP) | 2013-05-23 | — | — | US | disclosed |
| US-20130096339-A1 | METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE | API CORPORATION (JP) | 2013-04-18 | — | — | US | disclosed |
| EP-2537825-A1 | METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE | API Corporation (JP) | 2012-12-26 | — | — | EP | disclosed |
| CN-102834515-A | Novel hydrolase protein | API CORP | 2012-12-19 | — | — | CN | disclosed |
| WO-2012029819-A1 | NOVEL HYDROLASE PROTEIN | 株式会社エーピーアイ コーポレーション (JP) | 2012-03-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130096339-A1 | METHOD FOR PRODUCING 1-AMINO-1-ALKOXYCARBONYL-2-VINYLCYCLOPROPANE | HAVCR2, BCAT1, ALDH7A1 | ALDH1A1 76/4885NPSR1 3666/4885MAPK1 1498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.