Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 11/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54018 | 0.88 | CYP19A1 (0.59) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| Flusilazole SCHEMBL7049517 | 0.87 | CYP19A1 (0.49) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| Flusilazole SCHEMBL21313 | 0.87 | CYP19A1 (0.49) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| Flusilazole SCHEMBL8677611 | 0.87 | CYP19A1 (0.49) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10940035 | 0.81 | CYP19A1 (0.48) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL17018813 | 0.81 | CYP19A1 (0.44) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL11032944 | 0.81 | CYP19A1 (0.48) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9676982 | 0.78 | CYP19A1 (0.49) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9676996 | 0.78 | CYP19A1 (0.51) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9677119 | 0.78 | CYP19A1 (0.51) | CYP19A1KMT2ACYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305161-A1 | COMBINATIONS OF FUNGICIDAL AZOLES AND PYRION COMPOUNDS | BOSSELAERS JAN PETER HENDRIK | 2010-12-02 | — | — | US | disclosed |
| EP-2224814-A2 | COMBINATIONS OF FUNGICIDAL AZOLES AND PYRION COMPOUNDS | Janssen Pharmaceutica, N.V. (BE) | 2010-09-08 | — | — | EP | disclosed |
| US-7662748-B2 | Such as azaconazole, bromuconazole, and N,N',N'-tris(2-hydroxyethyl)-N-cocoalkyl-1,3-diamino-propane; kits; for protection of crops, plants, fruits, seeds, wood products, thatch, biodegradable material and textiles | JANSSEN PHARMACEUTICA, N.V. (BE) | 2010-02-16 | — | — | US | disclosed |
| WO-2009068606-A2 | COMBINATIONS OF FUNGICIDAL TRIAZOLES AND PYRION COMPOUNDS | JANSSEN PHARMACEUTICA NV (BE) | 2009-06-04 | — | — | WO | disclosed |
| US-20050080089-A1 | Formulations comprising triazoles and alkoxylated amines | AKZO NOBEL CHEMICALS BV (NL) | 2005-04-14 | — | — | US | disclosed |
| EP-1473996-A1 | FORMULATIONS COMPRISING TRIAZOLES AND ALKOXYLATED AMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 2004-11-10 | — | — | EP | disclosed |
| WO-2003065807-A1 | FORMULATIONS COMPRISING TRIAZOLES AND ALKOXYLATED AMINES | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080089-A1 | Formulations comprising triazoles and alkoxylated amines | ALKBH3, TYR, NAT1 | CYP19A1 1192/4885KMT2A 1163/4885CYP3A4 100/4885 |
| US-20100305161-A1 | COMBINATIONS OF FUNGICIDAL AZOLES AND PYRION COMPOUNDS | PPOX, PNPO, CYP3A43 | CYP19A1 734/4885KMT2A 4343/4885CYP3A4 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.