Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30076265 | 0.99 | HSD17B10 (0.48) | HSD17B10MAPTTSHRHTTSMN1; SMN2 | |
| SCHEMBL30076376 | 0.95 | ALDH1A1 (0.47) | HSD17B10MAPTTSHRHTTSMN1; SMN2 | |
| SCHEMBL21774320 | 0.85 | KDM4E (0.47) | HSD17B10MAPTTSHRHTTSMN1; SMN2 | |
| SCHEMBL21774352 | 0.84 | KDM4E (0.48) | HSD17B10MAPTTSHRHTTSMN1; SMN2 | |
| SCHEMBL21774357 | 0.82 | ALDH1A1 (0.51) | MAPTTSHRHTTSMN1; SMN2HPGD | |
| SCHEMBL21774368 | 0.81 | ALDH1A1 (0.46) | MAPTSMN1; SMN2ALDH1A1L3MBTL1ATM | |
| SCHEMBL21774129 | 0.80 | ALDH1A1 (0.49) | MAPTHTTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL21774134 | 0.80 | NTRK1 (0.50) | MAPTTSHRHTTALDH1A1L3MBTL1 | |
| SCHEMBL21774351 | 0.79 | ALDH1A1 (0.47) | MAPTTSHRHTTALDH1A1L3MBTL1 | |
| SCHEMBL28361285 | 0.78 | LMNA (0.56) | HSD17B10MAPTTSHRHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110857285-B | Substituted pyrazole compound, preparation method, pharmaceutical composition and application thereof | 江苏万高药业股份有限公司 | 2022-12-20 | — | — | CN | disclosed |