Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 4/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30079659 | 0.84 | PNMT (0.41) | PNMTNPC1RAB9AKLK1 | |
| SCHEMBL29897120 | 0.83 | PNMT (0.42) | PNMTNPC1RAB9A | |
| SCHEMBL7984404 | 0.82 | PNMT (0.38) | PNMTNPC1RAB9AATMCTSL | |
| SCHEMBL30762790 | 0.80 | PNMT (0.44) | PNMTNPC1RAB9ACTSLCTSS | |
| SCHEMBL22804044 | 0.80 | PNMT (0.44) | PNMTNPC1RAB9ACTSLCTSS | |
| SCHEMBL8303924 | 0.80 | PNMT (0.44) | PNMTNPC1RAB9ACTSLCTSS | |
| SCHEMBL6520232 | 0.80 | PNMT (0.44) | PNMTNPC1RAB9A | |
| SCHEMBL5689687 | 0.80 | PNMT (0.44) | PNMTNPC1RAB9ACTSLCTSS | |
| SCHEMBL6502789 | 0.80 | PNMT (0.54) | PNMTNPC1RAB9AMEN1KMT2A | |
| SCHEMBL6520215 | 0.80 | PNMT (0.46) | PNMTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109593068-B | Intermediate of ROR gamma inhibitor and preparation method thereof | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |