Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KLK1 | P06870 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | SDCBP | O00560 | 1/20 | 0.34 |
| ▸ | SDC2 | P34741 | 1/20 | 0.34 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7981681 | 0.91 | CTSL (0.37) | PNMTRAB9ANPC1CTSLCTSS | |
| SCHEMBL22804105 | 0.89 | TYR (0.43) | PNMTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL9052782 | 0.89 | TYR (0.43) | PNMTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL30762664 | 0.89 | TYR (0.43) | PNMTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL3727529 | 0.89 | TYR (0.43) | PNMTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL7980314 | 0.88 | CXCR2 (0.37) | PNMTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL7294513 | 0.88 | PNMT (0.41) | PNMTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL2551437 | 0.88 | CTSL (0.43) | PNMTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL2551443 | 0.88 | CTSL (0.43) | PNMTRAB9ANPC1MEN1KMT2A | |
| SCHEMBL22804056 | 0.86 | CYP2C9 (0.47) | PNMTRAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6284912-B1 | Process for synthesizing para-and/or meta-substituted cyanophenyalanine derivatives | LG CHEMICAL, LTD. (KR) | 2001-09-04 | — | — | US | disclosed |
| EP-1043309-A1 | Process for synthesizing para-and/or meta-substituted cyanophenylalanine derivatives | LG Chemical Ltd. (KR) | 2000-10-11 | — | — | EP | disclosed |