Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PPIA | P62937 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388659 | 1.00 | MAOB (0.38) | MAOBHSD17B10KDM4EMEN1HSP90AA1 | |
| SCHEMBL21893208 | 0.93 | PDE4B (0.35) | HSD17B10MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL30079621 | 0.84 | MAOB (0.36) | MAOBHSD17B10KDM4EMEN1HSP90AA1 | |
| SCHEMBL21893260 | 0.84 | MAOB (0.36) | MAOBHSD17B10KDM4EMEN1HSP90AA1 | |
| SCHEMBL21893167 | 0.83 | CYP2B6 (0.39) | MAOBHSD17B10KDM4EMEN1HSP90AA1 | |
| SCHEMBL30079767 | 0.82 | P2RX3 (0.36) | MAOBHSD17B10KDM4EMEN1HSP90AA1 | |
| SCHEMBL30079774 | 0.81 | F2 (0.34) | MAOBHSD17B10KDM4EPPIAALDH1A1 | |
| SCHEMBL21893148 | 0.77 | MAOB (0.33) | MAOBHSD17B10KDM4EMEN1KMT2A | |
| SCHEMBL21893267 | 0.77 | NOTUM (0.35) | HSD17B10HPGDPDE4B | |
| SCHEMBL29940702 | 0.77 | NOTUM (0.35) | HSD17B10HPGDPDE4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110964023-B | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2022-12-27 | — | — | CN | disclosed |