Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.33 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.33 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28388659 | 0.93 | MAOB (0.38) | PDE4BHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL30079834 | 0.93 | MAOB (0.38) | PDE4BHPGDALDH1A1HSD17B10MEN1 | |
| SCHEMBL29940702 | 0.84 | NOTUM (0.35) | PDE4BLMNAHPGDNOTUMHSD17B10 | |
| SCHEMBL21893267 | 0.84 | NOTUM (0.35) | PDE4BLMNAHPGDNOTUMHSD17B10 | |
| SCHEMBL21894040 | 0.81 | PDE4B (0.33) | PDE4BMEN1KMT2ACHRNA7 | |
| SCHEMBL29940674 | 0.81 | PDE4B (0.33) | PDE4BMEN1KMT2ACHRNA7 | |
| SCHEMBL18459475 | 0.78 | GPR84 (0.44) | PDE4BHPGDSRD5A1SRD5A2SMPD1 | |
| SCHEMBL21893260 | 0.77 | MAOB (0.36) | HPGDALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL30079621 | 0.77 | MAOB (0.36) | HPGDALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL28391592 | 0.76 | PDE4B (0.33) | PDE4BHSD17B10CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220041614-A1 | FUSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2022-02-10 | — | — | US | disclosed |
| WO-2020063870-A1 | FUSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2020-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220041614-A1 | FUSED TETRACYCLIC COMPOUNDS AND USES THEREOF IN MEDICINE | SLC10A1, CYP4A11, CYP11B2 | PDE4B 2755/4885LMNA 1375/4885HPGD 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.