Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 20/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080017 | 0.81 | GRM5 (0.42) | GRM5 | |
| SCHEMBL30079992 | 0.80 | GRM5 (0.38) | GRM5 | |
| SCHEMBL22275607 | 0.69 | CDK4 (0.34) | GRM5 | |
| SCHEMBL4092297 | 0.67 | MGLL (0.44) | — | |
| SCHEMBL22275392 | 0.66 | KDM4C (0.37) | — | |
| SCHEMBL22275240 | 0.66 | KDM4C (0.37) | — | |
| SCHEMBL22275447 | 0.66 | KDM4C (0.37) | — | |
| SCHEMBL15244394 | 0.64 | PTGS2 (0.36) | — | |
| SCHEMBL10394025 | 0.63 | MEN1 (0.39) | — | |
| SCHEMBL20400267 | 0.61 | MEN1 (0.45) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204036-B | Macrocyclic fused pyrazoles as MCL-1 inhibitors | 苏州亚盛药业有限公司 | 2022-12-27 | — | — | CN | disclosed |