Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TARBP2 | Q15633 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30487833 | 0.85 | TARBP2 (0.40) | KDM4EALDH1A1CYP1A2HPGDTARBP2 | |
| SCHEMBL5801249 | 0.85 | LMNA (0.44) | KDM4EALDH1A1CYP1A2HPGDTARBP2 | |
| SCHEMBL23986023 | 0.81 | HDAC4 (0.42) | KDM4ECYP1A2HPGDTARBP2HTT | |
| SCHEMBL6873803 | 0.81 | HPGD (0.43) | KDM4EALDH1A1CYP1A2POLBHPGD | |
| SCHEMBL8920076 | 0.79 | CA12 (0.46) | KDM4EALDH1A1CYP1A2HPGDTARBP2 | |
| SCHEMBL22727456 | 0.78 | TARBP2 (0.44) | KDM4EALDH1A1CYP1A2POLBHPGD | |
| SCHEMBL26921830 | 0.78 | HTT (0.46) | KDM4EALDH1A1CYP1A2HPGDTARBP2 | |
| SCHEMBL30173675 | 0.77 | HDAC4 (0.42) | KDM4EALDH1A1HPGDTARBP2HTT | |
| SCHEMBL23990453 | 0.77 | CYP1A2 (0.42) | KDM4EALDH1A1CYP1A2HPGDTARBP2 | |
| SCHEMBL16571753 | 0.77 | HTT (0.48) | ALDH1A1POLBHPGDTARBP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110650955-B | Compounds for the treatment of epilepsy, neurodegenerative disorders and other CNS disorders | 瑞敏德股份有限公司 | 2023-07-25 | — | — | CN | disclosed |
| CN-112204036-B | Macrocyclic fused pyrazoles as MCL-1 inhibitors | 苏州亚盛药业有限公司 | 2022-12-27 | — | — | CN | disclosed |