Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | MLYCD | O95822 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23986023 | 0.95 | HDAC4 (0.42) | HDAC4HDAC6KDM4EMLYCDHDAC3 | |
| SCHEMBL23985724 | 0.86 | DPP4 (0.30) | — | |
| SCHEMBL25414685 | 0.80 | NPSR1 (0.37) | KDM4EHDAC1MAPTALDH1A1KMT2A | |
| SCHEMBL30080002 | 0.77 | KDM4E (0.41) | KDM4ETARBP2HPGDMAPTHTT | |
| SCHEMBL5801249 | 0.76 | LMNA (0.44) | KDM4ETARBP2HPGDMAPTHTT | |
| SCHEMBL30487833 | 0.76 | TARBP2 (0.40) | KDM4ETARBP2HPGDMAPTHTT | |
| SCHEMBL31624362 | 0.76 | DPP4 (0.31) | — | |
| SCHEMBL3630512 | 0.75 | HDAC4 (0.44) | HDAC4HDAC6KDM4EMLYCDHDAC3 | |
| SCHEMBL8957137 | 0.74 | KDM4E (0.46) | HDAC4HDAC6KDM4ECYP2C9CYP2C19 | |
| SCHEMBL8920076 | 0.74 | CA12 (0.46) | KDM4ECYP2C19TARBP2HPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4143193-A1 | IMIDAZOPYRIMIDINES AS MODULATORS OF IL-17 | JANSSEN Pharmaceutica NV (BE) | 2023-03-08 | — | — | EP | disclosed |