Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | TDO2 | P48775 | 2/20 | 0.50 |
| ▸ | ACP3 | P15309 | 2/20 | 0.49 |
| ▸ | PNMT | P11086 | 1/20 | 0.45 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3156799 | 0.79 | PNMT (0.50) | IDO1TDO2ACP3PNMTDAO | |
| SCHEMBL686457 | 0.79 | IDO1 (0.56) | IDO1TDO2ACP3PNMTDAO | |
| SCHEMBL28479285 | 0.77 | IDO1 (0.46) | IDO1TDO2CES2EPHX1 | |
| SCHEMBL28479284 | 0.77 | IDO1 (0.46) | IDO1TDO2CES2EPHX1 | |
| SCHEMBL5139427 | 0.77 | PNMT (0.51) | IDO1TDO2ACP3PNMTDAO | |
| SCHEMBL2587951 | 0.77 | PNMT (0.51) | IDO1TDO2ACP3PNMTDAO | |
| SCHEMBL2601113 | 0.76 | DAO (0.59) | IDO1TDO2ACP3PNMTDAO | |
| SCHEMBL255035 | 0.76 | PNMT (0.55) | IDO1TDO2ACP3PNMTDAO | |
| SCHEMBL683709 | 0.76 | IDO1 (0.53) | IDO1TDO2ACP3PNMTDAO | |
| SCHEMBL10913587 | 0.76 | IDO1 (0.57) | IDO1TDO2ACP3PNMTDAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111203276-B | Application of chiral bidentate phosphite ligand, hydrosilation reaction catalyst and application thereof, and preparation method of chiral silane | 郑州大学 | 2022-11-18 | — | — | CN | disclosed |