Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.55 |
| ▸ | HTR2A | P28223 | 2/20 | 0.52 |
| ▸ | HTR2B | P41595 | 2/20 | 0.52 |
| ▸ | HTR2C | P28335 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | TDO2 | P48775 | 1/20 | 0.51 |
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.50 |
| ▸ | ACP3 | P15309 | 2/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ammonia Solution, Strong SCHEMBL27629775 | 0.98 | PNMT (0.53) | PNMTHTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL4784095 | 0.89 | DAO (0.48) | PNMTHTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL2662570 | 0.88 | PTPN5 (0.65) | PNMTHTR2AHTR2BHTR2CDAO | |
| SCHEMBL2601113 | 0.87 | DAO (0.59) | PNMTHTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL23343776 | 0.85 | PNMT (0.53) | PNMTHTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL7336199 | 0.85 | PNMT (0.53) | PNMTHTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL23590454 | 0.85 | PTPN5 (0.49) | PNMTHTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL10199855 | 0.85 | PTPN5 (0.49) | PNMTHTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL22189207 | 0.84 | PNMT (0.56) | PNMTHTR2AHTR2BHTR2CIDO1 | |
| SCHEMBL14020503 | 0.84 | PPARG (0.51) | HTR2AHTR2BHTR2CIDO1TDO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1313 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1219608-A1 | PYRIMIDINE DERIVATIVES, PROCESS FOR PREPARING THE DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-07-03 | — | — | EP | claimed |
| US-4436941-A | Process for the isomerization of alkylbenzotrifluorides | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | claimed |
| US-20240239772-A1 | PROTEASE INHIBITORS AND METHODS OF USE | THE CLEVELAND CLINIC FOUNDATION | 2024-07-18 | — | — | US | disclosed |
| US-12037323-B2 | Uracil derivatives as Mer-AXL inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-12037323-B2 | Uracil derivatives as Mer-AXL inhibitors | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-07-16 | — | — | US | disclosed |
| US-20240228535-A1 | PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION | MERCK SHARP & DOHME LLC (US) | 2024-07-11 | — | — | US | disclosed |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | Ikena Oncology, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | Ikena Oncology, Inc. (US) | 2024-07-09 | — | — | US | disclosed |
| US-20240208993-A1 | FIVE- AND SIX-MEMBERED COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | HANGZHOU POLYMED BIOPHARMACEUTICALS, INC. (CN) | 2024-06-27 | — | — | US | disclosed |
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | DICE MOLECULES SV, INC. | 2024-06-27 | — | — | US | disclosed |
| EP-0635485-A1 | TETRAHYDROPHTHALAMIDE DERIVATIVE, INTERMEDIATE FOR PRODUCING THE SAME, PRODUCTION OF BOTH, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1995-01-25 | — | — | EP | disclosed |
| US-4749813-A | 4-alkyl-2-trifluoromethylanilines | BAYER AKTIENGESELLSCHAFT (DE) | 1988-06-07 | — | — | US | disclosed |
| EP-0084128-B1 | PROCESS FOR THE PREPARATION OF ALKYLBENZENES SUBSTITUTED BY RADICALS CONTAINING FLUORINE | BAYER AG (DE) | 1987-01-21 | — | — | EP | disclosed |
| EP-0084320-B1 | 4-ALKYL-2-TRIFLUOROMETHYL ANILINES | BAYER AG (DE) | 1985-08-28 | — | — | EP | disclosed |
| EP-0084648-B1 | PROCESS FOR THE ISOMERIZATION OF ALKYLBENZOTRIFLUORIDES | BAYER AG (DE) | 1984-11-07 | — | — | EP | disclosed |
| US-4436941-A | Process for the isomerization of alkylbenzotrifluorides | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-13 | — | — | US | disclosed |
| EP-0084648-A1 | Process for the isomerization of alkylbenzotrifluorides | BAYER AG (DE) | 1983-08-03 | — | — | EP | disclosed |
| EP-0084320-A2 | 4-Alkyl-2-trifluoromethyl anilines | BAYER AG (DE) | 1983-07-27 | — | — | EP | disclosed |
| EP-0084128-A1 | Process for the preparation of alkylbenzenes substituted by radicals containing fluorine | BAYER AG (DE) | 1983-07-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240208968-A1 | ALPHA V BETA 6 AND ALPHA V BETA 1 INTEGRIN INHIBITORS AND USES THEREOF | ITGB1, ITGA1, ITGAV | PNMT 3195/4885HTR2A 3854/4885HTR2B 3181/4885 |
| US-20240228535-A1 | PROTEASE INHIBITORS FOR TREATING OR PREVENTING CORONAVIRUS INFECTION | PRSS1, PRSS2, ACE2 | PNMT 3650/4885HTR2A 3400/4885HTR2B 2462/4885 |
| US-12037323-B2 | Uracil derivatives as Mer-AXL inhibitors | MERTK, DAPK1, AXL | PNMT 4000/4885HTR2A 4075/4885HTR2B 4475/4885 |
| US-12030876-B2 | Aryl hydrocarbon receptor (AHR) agonists and uses thereof | AHR, ARNT, HCAR1 | PNMT 1402/4885HTR2A 194/4885HTR2B 259/4885 |
| US-20240208993-A1 | FIVE- AND SIX-MEMBERED COMPOUND, AND PREPARATION METHOD THEREFOR AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | IRAK4, FLT3, IRAK2 | PNMT 4642/4885HTR2A 4349/4885HTR2B 2584/4885 |
| US-20240239772-A1 | PROTEASE INHIBITORS AND METHODS OF USE | ACE2, ACE, TMPRSS2 | PNMT 3053/4885HTR2A 2198/4885HTR2B 2176/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.