Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 4/20 | 0.45 |
| ▸ | GRB2 | P62993 | 1/20 | 0.43 |
| ▸ | BDKRB2 | P30411 | 4/20 | 0.41 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | RAMP3 | O60896 | 3/20 | 0.39 |
| ▸ | CALCR | P30988 | 3/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31259022 | 0.94 | CAPN1 (0.52) | OPRM1OPRD1CAPN1GRB2BDKRB2 | |
| SCHEMBL29691873 | 0.93 | CAPN1 (0.47) | OPRM1OPRD1CAPN1GRB2BDKRB2 | |
| SCHEMBL30307615 | 0.92 | OPRM1 (0.46) | OPRM1OPRD1CAPN1GRB2BDKRB2 | |
| SCHEMBL30167004 | 0.91 | CAPN1 (0.46) | OPRM1OPRD1CAPN1GRB2BDKRB2 | |
| SCHEMBL29376366 | 0.91 | CAPN1 (0.46) | OPRM1OPRD1CAPN1GRB2BDKRB2 | |
| SCHEMBL29375301 | 0.91 | CAPN1 (0.46) | OPRM1OPRD1CAPN1GRB2BDKRB2 | |
| SCHEMBL30139026 | 0.90 | OPRM1 (0.46) | OPRM1OPRD1CAPN1GRB2XIAP | |
| SCHEMBL30626180 | 0.89 | OPRM1 (0.51) | OPRM1OPRD1CAPN1GRB2BDKRB2 | |
| SCHEMBL29397180 | 0.89 | OPRM1 (0.51) | OPRM1OPRD1CAPN1GRB2BDKRB2 | |
| SCHEMBL29554130 | 0.89 | CAPN1 (0.47) | OPRM1OPRD1CAPN1GRB2BDKRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120425-A | GLP-1/GIP receptor dual agonist and application thereof | 南京赛诺生物技术有限公司 | 2023-05-16 | — | — | CN | claimed |
| CN-115594752-A | Long-acting double-agonist compound | 成都奥达生物科技有限公司（CN） | 2023-01-13 | — | — | CN | claimed |
| CN-116120425-A | GLP-1/GIP receptor dual agonist and application thereof | 南京赛诺生物技术有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-115594753-A | Long-acting double-agonist compound | 成都奥达生物科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |