Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 18/20 | 0.52 |
| ▸ | DRD3 | P35462 | 18/20 | 0.52 |
| ▸ | HTR1A | P08908 | 5/20 | 0.51 |
| ▸ | HTR2A | P28223 | 5/20 | 0.51 |
| ▸ | HTR2C | P28335 | 5/20 | 0.51 |
| ▸ | DRD4 | P21917 | 1/20 | 0.51 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30080729 | 0.94 | DRD2 (0.51) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL28933676 | 0.84 | NTRK1 (0.62) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL30080769 | 0.81 | DRD3 (0.73) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL2316307 | 0.80 | DRD2 (0.55) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL2318622 | 0.80 | DRD2 (0.51) | DRD2DRD3HTR1AHTR2AHTR2C | |
| SCHEMBL2314670 | 0.69 | ALDH1A1 (0.67) | HTR1A | |
| SCHEMBL30080707 | 0.69 | ALDH1A1 (0.67) | HTR1A | |
| SCHEMBL2314674 | 0.69 | ALDH1A1 (0.67) | HTR1A | |
| SCHEMBL2316128 | 0.69 | ALDH1A1 (0.67) | HTR1A | |
| SCHEMBL8919663 | 0.68 | SMYD3 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109419802-B | Compounds having dopamine D3 receptor modulating activity and uses thereof | 中国人民解放军军事医学科学院毒物药物研究所（CN） | 2023-01-13 | — | — | CN | disclosed |