Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.50 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.47 |
| ▸ | MPO | P05164 | 2/20 | 0.46 |
| ▸ | XDH | P47989 | 2/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28314220 | 1.00 | KDM4E (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL31664560 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL28688074 | 0.83 | MAPK10 (0.44) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL19146396 | 0.81 | NQO2 (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL5473245 | 0.79 | NQO2 (0.54) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL24391685 | 0.76 | KDM4E (0.51) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL28445737 | 0.76 | KDM4E (0.71) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL6678538 | 0.75 | AR (0.57) | KDM4EALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL31195781 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT | |
| SCHEMBL7983948 | 0.74 | KDM4E (0.61) | KDM4EALDH1A1HPGDSMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115362150-A | ENPP1 inhibitor, composition and application thereof | 贝达药业股份有限公司 | 2022-11-18 | — | — | CN | disclosed |