Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | RAB9A | P51151 | 6/20 | 0.42 |
| ▸ | NPC1 | O15118 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resomelagon SCHEMBL12123680 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL23716726 | 1.00 | ALDH1A1 (0.43) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL30064309 | 0.98 | ALDH1A1 (0.42) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL30862151 | 0.96 | RAB9A (0.44) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL30853066 | 0.95 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL28929658 | 0.95 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL22658047 | 0.95 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL30084718 | 0.93 | NPC1 (0.44) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL30084719 | 0.93 | MAPT (0.41) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A | |
| Resomelagon SCHEMBL30065231 | 0.92 | ALDH1A1 (0.45) | ALDH1A1MAPTSMN1; SMN2GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359076-A1 | PHENYL PYRROLE AMINOGUANIDINE SALTS AND FORMULATIONS | SynAct Pharma ApS (DK) | 2024-05-01 | — | — | EP | disclosed |
| EP-4359383-A1 | SALTS OF PHENYL PYRROLE AMINOGUANIDINE AND POLYMORPHS OF PHENYL PYRROLE AMINOGUANIDINIUM SALTS | SynAct Pharma ApS (DK) | 2024-05-01 | — | — | EP | disclosed |
| WO-2022268814-A1 | SALTS OF PHENYL PYRROLE AMINOGUANIDINE AND POLYMORPHS OF PHENYL PYRROLE AMINOGUANIDINIUM SALTS | SYNACT PHARMA APS (DK) | 2022-12-29 | — | — | WO | disclosed |
| WO-2022268825-A1 | PHENYL PYRROLE AMINOGUANIDINE SALTS AND FORMULATIONS | SYNACT PHARMA APS (DK) | 2022-12-29 | — | — | WO | disclosed |