Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.44 |
| ▸ | NPY4R | P50391 | 11/20 | 0.42 |
| ▸ | NPY1R | P25929 | 6/20 | 0.42 |
| ▸ | NPY2R | P49146 | 4/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 4/20 | 0.42 |
| ▸ | FURIN | P09958 | 3/20 | 0.37 |
| ▸ | FNTA | P49354 | 1/20 | 0.37 |
| ▸ | FNTB | P49356 | 1/20 | 0.37 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.37 |
| ▸ | NRP1 | O14786 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31031459 | 0.92 | NOD1 (0.42) | NOD1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30774293 | 0.91 | EPHX2 (0.38) | NOD1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL30198545 | 0.90 | TFPI (0.45) | NPY4RNPY1RNPY2RNPY5RFURIN | |
| SCHEMBL30786591 | 0.90 | NPY4R (0.48) | NOD1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL27632326 | 0.89 | NOD1 (0.51) | NOD1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL27632323 | 0.89 | NOD1 (0.51) | NOD1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11206495 | 0.88 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL11206486 | 0.88 | NPY4R (0.54) | NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL6850341 | 0.88 | FURIN (0.40) | NOD1NPY4RNPY1RNPY2RNPY5R | |
| SCHEMBL6850333 | 0.88 | FURIN (0.40) | NOD1NPY4RNPY1RNPY2RNPY5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4355373-A1 | COMPOSITION AND USE OF SIRNAS AGAINST VEGFR2 AND TGF-BETA1 IN COMBINATION THERAPY FOR CANCER | Sirnaomics, Inc. (US) | 2024-04-24 | — | — | EP | disclosed |
| WO-2023288141-A1 | COMPOSITION AND USE OF SIRNAS AGAINST VEGFR2 AND TGF-BETA1 IN COMBINATION THERAPY FOR CANCER | SIRNAOMICS, INC. (US) | 2023-01-19 | — | — | WO | disclosed |