Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KLKB1 | P03952 | 4/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 5/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754188 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL23768900 | 1.00 | ALDH1A1 (0.48) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL23769282 | 0.93 | ALDH1A1 (0.49) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL31033209 | 0.89 | KLKB1 (0.56) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL20541015 | 0.89 | KLKB1 (0.56) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL23769155 | 0.89 | ALDH1A1 (0.50) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL31357759 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL23754180 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL23769308 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD | |
| SCHEMBL23753965 | 0.88 | ALDH1A1 (0.52) | ALDH1A1LMNAKLKB1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120287-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2025-01-28 | — | — | CN | disclosed |
| EP-4103562-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2022-12-21 | — | — | EP | disclosed |