Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RBP4 | P02753 | 9/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.35 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23754327 | 1.00 | RBP4 (0.36) | RBP4KLKB1PDE5AHDAC3CYP2D6 | |
| SCHEMBL23769185 | 0.89 | KLKB1 (0.35) | RBP4KLKB1PDE5A | |
| SCHEMBL23769275 | 0.81 | KLKB1 (0.60) | KLKB1 | |
| SCHEMBL21736743 | 0.80 | KLKB1 (0.49) | RBP4KLKB1 | |
| SCHEMBL23753966 | 0.80 | RBP4 (0.35) | RBP4PDE5AHDAC3CYP2D6HDAC4 | |
| SCHEMBL23769221 | 0.78 | KLKB1 (0.45) | RBP4KLKB1 | |
| SCHEMBL23769396 | 0.75 | KLKB1 (0.44) | RBP4KLKB1 | |
| SCHEMBL23769211 | 0.74 | KLKB1 (0.38) | KLKB1PDE5A | |
| SCHEMBL23754159 | 0.73 | ALDH1A1 (0.45) | RBP4PDE5A | |
| SCHEMBL29906556 | 0.73 | ALDH1A1 (0.45) | RBP4PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116120287-B | Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein | 勃林格殷格翰国际有限公司 | 2025-01-28 | — | — | CN | disclosed |
| EP-4103562-A1 | HETEROAROMATIC CARBOXAMIDE DERIVATIVES AS PLASMA KALLIKREIN INHIBITORS | Boehringer Ingelheim International GmbH (DE) | 2022-12-21 | — | — | EP | disclosed |