Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 1.00 |
| ▸ | PTGS1 | P23219 | 1/20 | 1.00 |
| ▸ | PTGS2 | P35354 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bw-755C SCHEMBL2573191 | 1.00 | ALOX5 (1.00) | ALOX5PTGS1PTGS2MAPTGAA | |
| Bw-755C SCHEMBL1040411 | 0.98 | ALOX5 (0.97) | ALOX5PTGS1PTGS2MAPTGAA | |
| SCHEMBL10830542 | 0.85 | ALOX5 (0.74) | ALOX5PTGS1PTGS2MAPTGAA | |
| SCHEMBL10954928 | 0.81 | ALOX5 (0.68) | ALOX5PTGS1PTGS2MAPTGAA | |
| SCHEMBL908075 | 0.80 | ALOX5 (0.66) | ALOX5PTGS1PTGS2MAPTGAA | |
| SCHEMBL10917829 | 0.78 | MAPT (0.66) | ALOX5PTGS1PTGS2MAPTGAA | |
| SCHEMBL9813214 | 0.78 | ALOX5 (0.64) | ALOX5PTGS1PTGS2MAPTGAA | |
| Hydrochloric Acid SCHEMBL11114350 | 0.77 | ALOX5 (0.63) | ALOX5PTGS1PTGS2MAPTGAA | |
| SCHEMBL7721910 | 0.76 | ALOX5 (0.61) | ALOX5PTGS1PTGS2MAPTGAA | |
| SCHEMBL907934 | 0.76 | ABL1 (0.64) | ALOX5PTGS1PTGS2MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023119230-A1 | COAGULATION PATHWAY AND NICOTINAMIDE-ADENINE DINUCLEOTIDE PATHWAY MODULATING COMPOSITIONS AND METHODS OF THEIR USE | L'OREAL (FR) | 2023-06-29 | — | — | WO | disclosed |
| CN-115536649-A | Polysubstituted pyrazoline compound and synthesis method thereof | 四川普康药业有限公司 | 2022-12-30 | — | — | CN | disclosed |