Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL30089487

NC/C(=C/F)COc1ccc(C(=O)N2CCc3ccccc3C2)cc1F.O=C(O)C(F)(F)F

nearest known ligand 0.45

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.45
ALDH1A1 P00352 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
AOC3 Q16853 5/20 0.44
NPC1 O15118 2/20 0.43
KMT2A Q03164 4/20 0.42
MEN1 O00255 3/20 0.42
HSP90AA1 P07900 2/20 0.42
HSP90AB1 P08238 2/20 0.42
TP53 P04637 1/20 0.41
LOX P28300 1/20 0.41
LOXL2 Q9Y4K0 1/20 0.41
LMNA P02545 2/20 0.41
KDM4E B2RXH2 1/20 0.41
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
CA14 Q9ULX7 1/20 0.40
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL30089479 1.00 HPGD (0.45) HPGDALDH1A1SMN1; SMN2AOC3NPC1
Trifluoroacetic Acid SCHEMBL30089447 1.00 HPGD (0.45) HPGDALDH1A1SMN1; SMN2AOC3NPC1
SCHEMBL21780098 0.95 HPGD (0.50) HPGDALDH1A1SMN1; SMN2AOC3NPC1
SCHEMBL21780093 0.95 HPGD (0.50) HPGDALDH1A1SMN1; SMN2AOC3NPC1
Trifluoroacetic Acid SCHEMBL21768136 0.89 AOC2 (0.38) HPGDALDH1A1SMN1; SMN2AOC3NPC1
Trifluoroacetic Acid SCHEMBL21768123 0.89 AOC2 (0.38) HPGDALDH1A1SMN1; SMN2AOC3NPC1
Trifluoroacetic Acid SCHEMBL30089532 0.89 AOC2 (0.38) HPGDALDH1A1SMN1; SMN2AOC3NPC1
Trifluoroacetic Acid SCHEMBL21768048 0.89 AOC2 (0.38) HPGDALDH1A1SMN1; SMN2AOC3NPC1
Trifluoroacetic Acid SCHEMBL30089527 0.89 AOC2 (0.38) HPGDALDH1A1SMN1; SMN2AOC3NPC1
Trifluoroacetic Acid SCHEMBL21768084 0.87 AOC3 (0.52) HPGDAOC3LMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110352188-B Fluoroallylamine derivatives and use thereof 四川科伦博泰生物医药股份有限公司 2022-11-29 CN disclosed