Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL21768084

NCC(=CF)COc1ccc(C(=O)N2CCc3ccccc3C2)cc1.O=C(O)C(F)(F)F

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AOC3 Q16853 7/20 0.52
AOC2 O75106 4/20 0.51
GAA P10253 1/20 0.49
MAPT P10636 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
L3MBTL1 Q9Y468 1/20 0.49
MAOB P27338 3/20 0.48
MAOA P21397 2/20 0.48
DAO P14920 1/20 0.48
TAAR1 Q96RJ0 1/20 0.47
HPGD P15428 2/20 0.46
LMNA P02545 1/20 0.46
CA1 P00915 1/20 0.46
CA2 P00918 1/20 0.46
CA7 P43166 1/20 0.46
CA9 Q16790 1/20 0.46
CA14 Q9ULX7 1/20 0.46
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL21768159 1.00 AOC3 (0.52) AOC3AOC2GAAMAPTTDP1
Trifluoroacetic Acid SCHEMBL30089516 1.00 AOC3 (0.52) AOC3AOC2GAAMAPTTDP1
Trifluoroacetic Acid SCHEMBL21768080 1.00 AOC3 (0.52) AOC3AOC2GAAMAPTTDP1
SCHEMBL21780142 0.94 AOC2 (0.56) AOC3AOC2GAAMAPTTDP1
SCHEMBL21780132 0.94 AOC2 (0.56) AOC3AOC2GAAMAPTTDP1
Trifluoroacetic Acid SCHEMBL21768076 0.88 AOC3 (0.51) AOC3AOC2MAOBMAOACA1
Trifluoroacetic Acid SCHEMBL30089479 0.87 HPGD (0.45) AOC3HPGDLMNACA1CA2
Trifluoroacetic Acid SCHEMBL30089487 0.87 HPGD (0.45) AOC3HPGDLMNACA1CA2
Trifluoroacetic Acid SCHEMBL30089447 0.87 HPGD (0.45) AOC3HPGDLMNACA1CA2
SCHEMBL21780087 0.84 AOC3 (0.52) AOC3AOC2MAOBMAOACA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110352188-B Fluoroallylamine derivatives and use thereof 四川科伦博泰生物医药股份有限公司 2022-11-29 CN disclosed
US-20200087248-A1 Fluoroallylamine Derivative And Use Thereof SICHUAN KELUN-BIOTECH BIOPHARMACEUTICAL CO., LTD. (CN) 2020-03-19 US disclosed
EP-3617186-A1 FLUOROALLYLAMINE DERIVATIVE AND USE THEREOF Sichuan Kelun-Biotech Biopharmaceutical Co., Ltd. (CN) 2020-03-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200087248-A1 Fluoroallylamine Derivative And Use Thereof VAPB, VAPA, SLC28A1 AOC3 6/4885AOC2 16/4885GAA 237/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.