SCHEMBL30089944

SCHEMBL30089944

COc1ccc2oc(NC(O)=S)cc2c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.50
ALDH1A1 P00352 4/20 0.50
HPGD P15428 3/20 0.50
CA2 P00918 2/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA3 P07451 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA7 P43166 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
MAOB P27338 1/20 0.48
TAS1R3 Q7RTX0 3/20 0.48
TAS1R1 Q7RTX1 3/20 0.48
MAPT P10636 5/20 0.47
HSD17B10 Q99714 4/20 0.47
CASP1 P29466 3/20 0.47
TP53 P04637 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31044605 0.76 TAS1R3 (0.55) KDM4EALDH1A1HPGDCA2CA12
SCHEMBL9826735 0.75 TAS1R3 (0.52) KDM4EALDH1A1HPGDCA2CA12
Hydrochloric Acid SCHEMBL10458713 0.74 TAS1R3 (0.51) KDM4EALDH1A1HPGDCA2CA12
SCHEMBL8315780 0.73 TAS1R3 (0.55) KDM4EALDH1A1HPGDCA2CA12
SCHEMBL13980462 0.72 CYP2A6 (0.53) KDM4EALDH1A1HPGDCA2CA12
SCHEMBL7922363 0.71 TAS1R3 (0.52) KDM4EALDH1A1HPGDCA2CA12
SCHEMBL11402397 0.71 MAPT (0.67) KDM4EALDH1A1HPGDCA2CA12
SCHEMBL12301434 0.70 CYP2A6 (0.54) KDM4EALDH1A1HPGDCA2CA12
SCHEMBL29527237 0.70 KDM4E (0.66) KDM4EALDH1A1HPGDCA2CA12
SCHEMBL335319 0.70 KDM4E (0.66) KDM4EALDH1A1HPGDCA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022242629-A1 COMPOUND CONTAINING PHOSPHATE GROUP, PHARMACEUTICAL COMPOSITION CONTAINING SAME, PREPARATION METHOD THEREFOR AND USE THEREOF 上海日馨医药科技股份有限公司 2022-11-24 WO disclosed