Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 7/20 | 0.55 |
| ▸ | TAS1R1 | Q7RTX1 | 7/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | APP | P05067 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | FLT3 | P36888 | 1/20 | 0.49 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.48 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31044605 | 0.87 | TAS1R3 (0.55) | TAS1R3TAS1R1CA2APPALDH1A1 | |
| SCHEMBL5806070 | 0.83 | TAS1R3 (0.62) | TAS1R3TAS1R1CA2APPALDH1A1 | |
| SCHEMBL31060243 | 0.81 | FLT3 (0.71) | TAS1R3TAS1R1CA2ALDH1A1KDM4E | |
| SCHEMBL28328754 | 0.80 | ALDH1A1 (0.64) | CA2APPALDH1A1KDM4ECA12 | |
| SCHEMBL29527237 | 0.80 | KDM4E (0.66) | TAS1R3TAS1R1CA2ALDH1A1KDM4E | |
| SCHEMBL335319 | 0.80 | KDM4E (0.66) | TAS1R3TAS1R1CA2ALDH1A1KDM4E | |
| SCHEMBL1287553 | 0.80 | KDM4E (0.66) | TAS1R3TAS1R1CA2ALDH1A1KDM4E | |
| SCHEMBL8253528 | 0.80 | TAS1R3 (0.55) | TAS1R3TAS1R1CA2APPALDH1A1 | |
| Hydrochloric Acid SCHEMBL11498190 | 0.79 | KDM4E (0.64) | TAS1R3TAS1R1CA2ALDH1A1KDM4E | |
| SCHEMBL446971 | 0.79 | TAS1R3 (0.64) | TAS1R3TAS1R1CA2ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0528337-B1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO (JP) | 1999-10-20 | — | — | EP | disclosed |
| US-5296495-A | Antiallergens, antiinflammatory | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-03-22 | — | — | US | disclosed |
| EP-0528337-A1 | New thiazolylbenzofuran derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1993-02-24 | — | — | EP | disclosed |