Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.46 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22273087 | 1.00 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL451696 | 0.79 | LMNA (0.54) | ALDH1A1SMN1; SMN2MAPTHTTLMNA | |
| SCHEMBL13753864 | 0.79 | HPGD (0.68) | HPGDALDH1A1SMN1; SMN2MAPTHTT | |
| SCHEMBL14120823 | 0.79 | POLB (0.62) | ALDH1A1SMN1; SMN2MAPTLMNARAB9A | |
| SCHEMBL31055452 | 0.78 | HPGD (0.59) | HPGDALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL7249392 | 0.78 | POLB (0.54) | ALDH1A1MAPTHTTLMNARAB9A | |
| SCHEMBL1459847 | 0.77 | HPGD (0.58) | HPGDALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL14054136 | 0.76 | PTPRC (0.47) | HPGDALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2273935 | 0.75 | PRSS1 (0.56) | HPGDALDH1A1SMN1; SMN2MAPTRAB9A | |
| SCHEMBL6619861 | 0.75 | HPGD (0.56) | HPGDALDH1A1SMN1; SMN2MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166116-B | Amido bridged heterocyclic compound, and composition and application thereof | 北京赛特明强医药科技有限公司 | 2022-12-27 | — | — | CN | disclosed |