Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 6/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 4/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL451696 | 0.90 | LMNA (0.54) | POLBLMNAMAPTHTTNPC1 | |
| SCHEMBL7250345 | 0.85 | MAPK1 (0.71) | POLBLMNAMAPK1HDAC3HDAC1 | |
| SCHEMBL450259 | 0.85 | NPC1 (0.59) | POLBMAPTNPC1RAB9AMAPK1 | |
| SCHEMBL1233409 | 0.81 | POLB (0.81) | POLBLMNAMAPTHTTNPC1 | |
| SCHEMBL2631174 | 0.80 | L3MBTL1 (0.68) | POLBLMNAMAPTHTTNPC1 | |
| SCHEMBL28706039 | 0.80 | NPC1 (0.60) | POLBLMNAMAPTHTTNPC1 | |
| SCHEMBL28706800 | 0.80 | NPC1 (0.60) | POLBLMNAMAPTHTTNPC1 | |
| SCHEMBL1231643 | 0.80 | HDAC1 (0.70) | POLBLMNANPC1RAB9AHDAC3 | |
| SCHEMBL1888791 | 0.80 | HDAC1 (0.70) | POLBLMNANPC1RAB9AHDAC3 | |
| SCHEMBL1232687 | 0.80 | HDAC1 (0.70) | POLBLMNANPC1RAB9AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6630577-B2 | Useful for producing bioconjugates | PROLINX, INC. | 2003-10-07 | — | — | US | disclosed |
| EP-1264833-A2 | 1,2-Phenylenediboronic acid reagents and complexes | PROLINX, INC. (US) | 2002-12-11 | — | — | EP | disclosed |
| US-20020038004-A1 | 1,2-phenylenediboronic acid reagents and complexes | PROLINX, INC. | 2002-03-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020038004-A1 | 1,2-phenylenediboronic acid reagents and complexes | BCR, MGST1, SULT1E1 | POLB 1396/4885LMNA 4240/4885MAPT 4011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.