Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | GABRP | O00591 | 1/20 | 0.32 |
| ▸ | GABRD | O14764 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23833648 | 1.00 | ALDH1A1 (0.36) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL28658209 | 0.80 | MEN1 (0.35) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL20306631 | 0.78 | CHRNB2 (0.36) | ALDH1A1CHRNB2CHRNA4KMT2ADGAT1 | |
| SCHEMBL28862789 | 0.77 | MEN1 (0.31) | ALDH1A1MEN1KMT2ACYP1A2CYP2D6 | |
| SCHEMBL6050425 | 0.76 | MEN1 (0.39) | MEN1KMT2ACYP1A2CYP2D6CYP2C9 | |
| SCHEMBL30094537 | 0.75 | CHRNB2 (0.41) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL23833624 | 0.75 | CHRNB2 (0.41) | ALDH1A1CHRNB2CHRNA4MEN1KMT2A | |
| SCHEMBL30669490 | 0.74 | — | — | |
| SCHEMBL1644729 | 0.74 | — | — | |
| SCHEMBL29928048 | 0.72 | ALDH1A1 (0.31) | ALDH1A1MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4121426-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | Akebia Therapeutics Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| CN-115515948-A | PHD inhibitor compounds, compositions and uses | 阿克比治疗有限公司 | 2022-12-23 | — | — | CN | disclosed |