Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 8/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 7/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.35 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27246669 | 1.00 | CYP11B1 (0.40) | CYP11B1CYP11B2KCNH2KDM1AMAOA | |
| SCHEMBL15227173 | 0.80 | GRIN2D (0.46) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL27726738 | 0.76 | MAPK1 (0.43) | MAOAMAOBCYP1A2 | |
| SCHEMBL16401448 | 0.75 | TAAR1 (0.50) | MAOBGRIN1GRIN2B | |
| SCHEMBL30394051 | 0.75 | TAAR1 (0.50) | MAOBGRIN1GRIN2B | |
| SCHEMBL13805786 | 0.75 | GRIN2D (0.41) | GRIN1GRIN2BGRIN2DGRIN3BGRIN2A | |
| SCHEMBL15693699 | 0.75 | GRIN2D (0.41) | MAOBGRIN1GRIN2BGRIN2DGRIN3B | |
| SCHEMBL28083308 | 0.74 | ATM (0.50) | CYP11B1CYP11B2CYP2C9 | |
| SCHEMBL13587367 | 0.74 | KDM4E (0.33) | KCNH2 | |
| SCHEMBL13547438 | 0.73 | MIF (0.52) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117642397-A | Modified proteins and protein binders | 上海睿跃生物科技有限公司 | 2024-03-01 | — | — | CN | disclosed |
| WO-2022194087-A1 | MODIFIED PROTEINS AND PROTEIN BINDERS | CULLGEN (SHANGHAI) , INC. (CN) | 2022-09-22 | — | — | WO | disclosed |