Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | PPIA | P62937 | 2/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PPIF | P30405 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.48 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566106 | 1.00 | MAPT (0.60) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9687632 | 0.86 | MAPT (0.67) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9566105 | 0.85 | MAPT (0.56) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL214776 | 0.83 | MEN1 (0.62) | MAPTMEN1KMT2APPIACYP19A1 | |
| SCHEMBL14008900 | 0.83 | CYP19A1 (0.62) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL347674 | 0.79 | MEN1 (0.65) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL692555 | 0.79 | HTR1A (0.67) | MAPTLMNAMEN1KMT2AHTR1A | |
| SCHEMBL25204382 | 0.79 | MAPT (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6031737 | 0.79 | MAPT (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL13483785 | 0.79 | MAPT (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113817164-B | Hypoxic sensitive drug carrier polymer and preparation method and application thereof | 北京化工大学 | 2022-11-29 | — | — | CN | disclosed |