Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.67 |
| ▸ | LMNA | P02545 | 3/20 | 0.67 |
| ▸ | NPC1 | O15118 | 2/20 | 0.67 |
| ▸ | RAB9A | P51151 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 4/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.61 |
| ▸ | IDO1 | P14902 | 2/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | PPIA | P62937 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13483785 | 0.89 | MAPT (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6031737 | 0.89 | MAPT (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL25204382 | 0.89 | MAPT (0.59) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9566106 | 0.86 | MAPT (0.60) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6730910 | 0.86 | PPIA (0.55) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL3686701 | 0.86 | MAPT (0.71) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL347674 | 0.86 | MEN1 (0.65) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9566105 | 0.86 | MAPT (0.56) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30096056 | 0.86 | MAPT (0.60) | MAPTLMNANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL227098 | 0.84 | MAPT (0.71) | MAPTLMNARAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0472062-A1 | Beta-lactam compounds, and their production and use | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1992-02-26 | — | — | EP | disclosed |