SCHEMBL30096808

SCHEMBL30096808

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cnc2n1C/C=C/Cn1c(N)nc2cc(C(N)=O)ccc21

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.66
▸ TBK1 Q9UHD2 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27134522 1.00 STING1 (0.66) STING1TBK1
SCHEMBL26980684 1.00 STING1 (0.66) STING1TBK1
SCHEMBL21158072 0.95 STING1 (0.70) STING1TBK1
SCHEMBL30096847 0.95 STING1 (0.70) STING1TBK1
SCHEMBL27125617 0.95 STING1 (0.70) STING1TBK1
SCHEMBL22150350 0.92 STING1 (0.75) STING1TBK1
SCHEMBL21616389 0.91 STING1 (0.77) STING1TBK1
SCHEMBL29689500 0.91 STING1 (0.77) STING1TBK1
SCHEMBL22149041 0.89 STING1 (0.68) STING1TBK1
SCHEMBL22121341 0.89 STING1 (0.70) STING1TBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022247743-A1 COMPOUNDS AND THEIR USE AS VACCINE ADJUVANTS FULGENT GENETICS, INC. (US) 2022-12-01 — — WO disclosed
WO-2022246597-A1 IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS FOREVER MILLETS LIMITED (CN) 2022-12-01 — — WO disclosed
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