SCHEMBL30096847

SCHEMBL30096847

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)ccc2n1C/C=C/Cn1c(NC(=O)c2cc(C)nn2CC)nc2cc(C(N)=O)cnc21

nearest known ligand 0.70

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.70
▸ TBK1 Q9UHD2 1/20 0.70

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27125617 1.00 STING1 (0.70) STING1TBK1
SCHEMBL21158072 1.00 STING1 (0.70) STING1TBK1
SCHEMBL26980684 0.95 STING1 (0.66) STING1TBK1
SCHEMBL30096808 0.95 STING1 (0.66) STING1TBK1
SCHEMBL27134522 0.95 STING1 (0.66) STING1TBK1
SCHEMBL21616389 0.93 STING1 (0.77) STING1TBK1
SCHEMBL29689500 0.93 STING1 (0.77) STING1TBK1
SCHEMBL19451632 0.93 STING1 (0.81) STING1TBK1
SCHEMBL29702138 0.93 STING1 (0.81) STING1TBK1
SCHEMBL21156976 0.92 STING1 (0.61) STING1TBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022246597-A1 IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS FOREVER MILLETS LIMITED (CN) 2022-12-01 — — WO claimed
WO-2022247743-A1 COMPOUNDS AND THEIR USE AS VACCINE ADJUVANTS FULGENT GENETICS, INC. (US) 2022-12-01 — — WO disclosed
WO-2022246597-A1 IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS FOREVER MILLETS LIMITED (CN) 2022-12-01 — — WO disclosed
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