SCHEMBL26980684

SCHEMBL26980684

CCn1nc(C)cc1C(=O)Nc1nc2cc(C(N)=O)cnc2n1C/C=C/Cn1c(N)nc2cc(C(N)=O)ccc21

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ STING1 Q86WV6 20/20 0.66
▸ TBK1 Q9UHD2 1/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30096808 1.00 STING1 (0.66) STING1TBK1
SCHEMBL27134522 1.00 STING1 (0.66) STING1TBK1
SCHEMBL21158072 0.95 STING1 (0.70) STING1TBK1
SCHEMBL30096847 0.95 STING1 (0.70) STING1TBK1
SCHEMBL27125617 0.95 STING1 (0.70) STING1TBK1
SCHEMBL22150350 0.92 STING1 (0.75) STING1TBK1
SCHEMBL21616389 0.91 STING1 (0.77) STING1TBK1
SCHEMBL29689500 0.91 STING1 (0.77) STING1TBK1
SCHEMBL22149041 0.89 STING1 (0.68) STING1TBK1
SCHEMBL22121341 0.89 STING1 (0.70) STING1TBK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240132493-A1 IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS FULGENT GENETICS INC (US) 2024-04-25 — — US disclosed
US-20240002383-A1 COMPOUNDS AND THEIR USE AS VACCINE ADJUVANTS FUDAN UNIVERSITY (CN) 2024-01-04 — — US disclosed
CN-116940574-A Compounds and their use as vaccine adjuvants 福君基因公司 2023-10-24 — — CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240002383-A1 COMPOUNDS AND THEIR USE AS VACCINE ADJUVANTS CTSA, ALOX5AP, ALOX15 STING1 4/4885TBK1 31/4885
US-20240132493-A1 IMIDAZOPYRIDINE DERIVATIVES AS STING AGONISTS STING1, IRF3, MAVS STING1 1/4885TBK1 5/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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