Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23832408 | 1.00 | FDFT1 (0.41) | FDFT1HPGDCYP19A1CHRNB2CHRNA4 | |
| SCHEMBL24899681 | 0.78 | FDFT1 (0.38) | FDFT1CHRNB2CHRNA4 | |
| SCHEMBL13536643 | 0.76 | HDAC1 (0.42) | HPGD | |
| SCHEMBL27037217 | 0.74 | NAPRT (0.41) | — | |
| SCHEMBL29849881 | 0.74 | CYP2A6 (0.34) | HPGD | |
| SCHEMBL21066301 | 0.74 | LMNA (0.42) | FDFT1 | |
| SCHEMBL24899842 | 0.72 | FDFT1 (0.37) | FDFT1CHRNB2CHRNA4 | |
| SCHEMBL23833609 | 0.71 | — | — | |
| SCHEMBL12091527 | 0.71 | HPGD (0.35) | HPGD | |
| SCHEMBL23832350 | 0.69 | KDM4E (0.42) | FDFT1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605467-B | PHD inhibitor compounds, compositions and uses thereof | 阿克比治疗有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-120004851-A | PHD inhibitor compounds, compositions and uses thereof | 阿克比治疗有限公司 | 2025-05-16 | — | — | CN | disclosed |
| EP-4121426-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND USE | Akebia Therapeutics Inc. (US) | 2023-01-25 | — | — | EP | disclosed |
| EP-4121424-A1 | PHD INHIBITOR COMPOUNDS, COMPOSITIONS, AND THEIR USE | Akebia Therapeutics Inc. (US) | 2023-01-25 | — | — | EP | disclosed |