SCHEMBL21066301

SCHEMBL21066301

O=P(c1ccccc1)(c1ccccc1)c1ccc(Br)nc1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 1/20 0.42
▸ FDFT1 P37268 1/20 0.41
▸ CA2 P00918 1/20 0.40
▸ CA4 P22748 1/20 0.40
▸ CA5A P35218 1/20 0.40
▸ MEN1 O00255 2/20 0.37
▸ KMT2A Q03164 2/20 0.37
▸ NPC1 O15118 2/20 0.35
▸ NFKB1 P19838 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ NFKB2 Q00653 2/20 0.35
▸ RELA Q04206 2/20 0.35
▸ SMN1; SMN2 Q16637 2/20 0.35
▸ KCNA5 P22460 3/20 0.35
▸ KCNN4 O15554 2/20 0.35
▸ ESR1 P03372 1/20 0.34
▸ ALDH1A1 P00352 1/20 0.33
▸ POLB P06746 1/20 0.33
▸ HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18577901 0.80 ESR1 (0.48) FDFT1NPC1NFKB1RAB9ANFKB2
SCHEMBL18577903 0.80 LMNA (0.40) LMNACA2CA4CA5AMEN1
SCHEMBL14076802 0.80 LMNA (0.44) LMNACA2CA4CA5AMEN1
SCHEMBL18577907 0.79 SMN1; SMN2 (0.46) LMNACA2CA4CA5AMEN1
SCHEMBL132983 0.76 LMNA (0.60) LMNACA2CA4CA5AMEN1
SCHEMBL5439069 0.76 LMNA (0.60) LMNACA2CA4CA5AMEN1
SCHEMBL5436616 0.76 LMNA (0.60) LMNACA2CA4CA5AMEN1
SCHEMBL6568180 0.74 ALDH1A1 (0.52) LMNACA2CA4CA5AMEN1
SCHEMBL2678331 0.74 ALDH1A1 (0.52) LMNACA2CA4CA5AMEN1
SCHEMBL23832408 0.74 FDFT1 (0.41) FDFT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10428269-B2 Indenotriphenylene derivative and organic electroluminescence device using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2019-10-01 — — US disclosed
US-20190194534-A1 INDENOTRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2019-06-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190194534-A1 INDENOTRIPHENYLENE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME ICMT, INCENP, ITPA LMNA 2838/4885FDFT1 1674/4885CA2 4179/4885
US-10428269-B2 Indenotriphenylene derivative and organic electroluminescence device using the same ICMT, INCENP, ITPA LMNA 2838/4885FDFT1 1674/4885CA2 4179/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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