Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 5/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 5/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.32 |
| ▸ | TAF1 | P21675 | 1/20 | 0.32 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23706219 | 1.00 | GAA (0.37) | GAABRD4ALOX15TSHRMAP2K1 | |
| SCHEMBL26141114 | 0.77 | EIF4A3 (0.38) | GAABRD4TP53BRD9BRD7 | |
| SCHEMBL18230155 | 0.77 | RHEB (0.40) | MAP2K1RXFP1MAP2K2 | |
| SCHEMBL29967388 | 0.77 | RHEB (0.40) | MAP2K1RXFP1MAP2K2 | |
| SCHEMBL30097011 | 0.76 | GAA (0.37) | GAABRD4TP53BRD9TAF1 | |
| SCHEMBL23706126 | 0.76 | GAA (0.37) | GAABRD4TP53BRD9TAF1 | |
| SCHEMBL31559897 | 0.76 | MAP2K1 (0.42) | BRD4ALOX15TSHRMAP2K1MAP2K2 | |
| SCHEMBL25898037 | 0.75 | TAF1 (0.38) | BRD4ALOX15TSHRMAP2K1EGFR | |
| SCHEMBL20292730 | 0.73 | GAA (0.56) | GAABRD4TP53 | |
| SCHEMBL9919029 | 0.71 | PSMB1 (0.46) | GAABRD4MAP2K1BRD9TAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115297861-B | Compounds and uses thereof | 福宏治疗公司 | 2024-07-12 | — | — | CN | disclosed |
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |