Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 4/20 | 0.35 |
| ▸ | TDO2 | P48775 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22408226 | 1.00 | IDO1 (0.35) | IDO1TDO2ALDH1A1GAAPOLB | |
| SCHEMBL21886096 | 0.86 | HRH4 (0.40) | IDO1TDO2ALDH1A1GAAPOLB | |
| SCHEMBL22408523 | 0.80 | KDM4E (0.41) | IDO1TDO2ALDH1A1GAAPOLB | |
| SCHEMBL22408039 | 0.77 | GAA (0.36) | IDO1TDO2ALDH1A1GAAPOLB | |
| SCHEMBL16005110 | 0.77 | ALDH1A1 (0.30) | ALDH1A1GAAPOLBMAPTRXFP1 | |
| SCHEMBL28352972 | 0.77 | ASH1L (0.44) | ALDH1A1GAAPOLBMAPTRXFP1 | |
| SCHEMBL22408139 | 0.74 | KEAP1 (0.34) | IDO1TDO2ALDH1A1GAAPOLB | |
| SCHEMBL22407931 | 0.74 | ALDH1A1 (0.36) | ALDH1A1GAAPOLBMAPTRXFP1 | |
| SCHEMBL22407908 | 0.74 | KDM4E (0.42) | IDO1TDO2GAAPOLBMAPT | |
| SCHEMBL15450918 | 0.74 | KDM4E (0.42) | ALDH1A1GAAPOLBMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |