Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 1/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15270885 | 1.00 | ALDH1A1 (0.56) | ALDH1A1HTTTSHRMAPTMAOA | |
| SCHEMBL3350981 | 0.90 | MAOB (0.65) | ALDH1A1HTTTSHRMAPTMAOA | |
| SCHEMBL31704227 | 0.88 | SMN1; SMN2 (0.49) | ALDH1A1HTTTSHRMAPTMAOA | |
| SCHEMBL15942268 | 0.84 | CASP3 (0.50) | ALDH1A1HTTTSHRMAPTMAOA | |
| SCHEMBL31393683 | 0.84 | MAOB (0.57) | ALDH1A1HTTTSHRMAOBCASP3 | |
| SCHEMBL9844024 | 0.84 | MAOB (0.57) | ALDH1A1HTTTSHRMAOBCASP3 | |
| SCHEMBL10899013 | 0.83 | MAOB (0.55) | ALDH1A1TSHRMAOAMAOBNR4A2 | |
| SCHEMBL17344322 | 0.82 | ALDH1A1 (0.62) | ALDH1A1HTTTSHRMAPTMAOA | |
| SCHEMBL12285212 | 0.82 | MAPT (0.50) | ALDH1A1HTTTSHRMAPTMAOA | |
| SCHEMBL10900438 | 0.81 | ALDH1A1 (0.54) | ALDH1A1HTTTSHRMAPTMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4096667-A1 | COMPOUNDS AND USES THEREOF | Foghorn Therapeutics Inc. (US) | 2022-12-07 | — | — | EP | disclosed |