SCHEMBL30099150

SCHEMBL30099150

CCOC(=O)c1sc2cc(C(F)(F)F)ccc2c1Cl

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.48
TP53 P04637 2/20 0.48
MAPT P10636 8/20 0.48
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
KDM4E B2RXH2 3/20 0.48
HSP90AA1 P07900 1/20 0.48
CRHBP P24387 1/20 0.48
CRHR2 Q13324 1/20 0.48
RXFP1 Q9HBX9 2/20 0.47
GAA P10253 2/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
BCL2L1 Q07817 1/20 0.46
MCL1 Q07820 1/20 0.46
ALDH1A1 P00352 3/20 0.44
HPGD P15428 1/20 0.44
NPSR1 Q6W5P4 2/20 0.43
CYP1A2 P05177 2/20 0.43
CYP2C9 P11712 2/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28836579 1.00 LMNA (0.48) LMNATP53MAPTMEN1KMT2A
SCHEMBL8136940 0.85 KDM4E (0.51) LMNATP53MAPTMEN1KMT2A
SCHEMBL8010663 0.83 BCL2L1 (0.67) LMNATP53MAPTKDM4ERXFP1
SCHEMBL28952691 0.82 LMNA (0.58) LMNATP53MAPTMEN1KMT2A
SCHEMBL28836319 0.82 MAPT (0.47) LMNATP53MAPTMEN1KMT2A
SCHEMBL31483496 0.81 MAPT (0.49) LMNATP53MAPTMEN1KMT2A
SCHEMBL6824033 0.81 MAPT (0.49) LMNATP53MAPTMEN1KMT2A
SCHEMBL8010924 0.81 MCL1 (0.52) LMNATP53MAPTMEN1KMT2A
SCHEMBL869233 0.80 BCKDK (0.50) LMNAMAPTKDM4ERXFP1GAA
SCHEMBL31194453 0.80 BCKDK (0.50) LMNAMAPTKDM4ERXFP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115023426-B Pesticidally active heterocyclic derivatives with sulfur containing substituents 先正达农作物保护股份公司 2024-11-12 CN disclosed
EP-4087841-A1 PESTICIDALLY ACTIVE HETEROCYCLIC DERIVATIVES WITH SULFUR CONTAINING SUBSTITUENTS Syngenta Crop Protection AG (CH) 2022-11-16 EP disclosed