Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | MCHR1 | Q99705 | 9/20 | 0.46 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.45 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.45 |
| ▸ | PAK4 | O96013 | 1/20 | 0.45 |
| ▸ | ABL1 | P00519 | 1/20 | 0.45 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.45 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | CSF1R | P07333 | 1/20 | 0.45 |
| ▸ | RET | P07949 | 1/20 | 0.45 |
| ▸ | MET | P08581 | 1/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.45 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.45 |
| ▸ | PRKACA | P17612 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16739619 | 0.86 | KDM4E (0.50) | SCN5AMCHR1CCNB2CCNE2CDK1 | |
| SCHEMBL10311041 | 0.84 | MCHR1 (0.52) | MCHR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL38662516 | 0.79 | MCHR1 (0.53) | SCN5AMCHR1KDM4EALDH1A1NPC1 | |
| SCHEMBL30845741 | 0.77 | EGLN1 (0.52) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL10053505 | 0.76 | MCHR1 (0.48) | MCHR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL18080888 | 0.75 | SCN5A (0.53) | SCN5AMCHR1TGFBR1KDM4EALDH1A1 | |
| SCHEMBL327269 | 0.74 | PTGS1 (0.54) | CHEK1AURKADAPK3JAK2PRKD3 | |
| SCHEMBL9570267 | 0.73 | CHEK1 (0.46) | MCHR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL9597339 | 0.73 | MCHR1 (0.50) | MCHR1CHEK1AURKADAPK3JAK2 | |
| SCHEMBL12056714 | 0.73 | SCN5A (0.54) | SCN5AMCHR1CDK5KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022255900-A1 | CYSTEINYL LEUKOTRIENE RECEPTOR LIGANDS DIRECTED TOWARD THE TREATMENT OF INFLAMMATORY AND ONCOLOGICAL DISEASES | федеральное государственное автономное образовательное учреждение высшего образования "Московский физико-технический институт (национальный исследовательский университет)" | 2022-12-08 | — | — | WO | disclosed |