Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TUBB | P07437 | 2/20 | 0.75 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.69 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.65 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 3/20 | 0.64 |
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | HTT | P42858 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.60 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | CDK1 | P06493 | 1/20 | 0.58 |
| ▸ | THRA | P10827 | 1/20 | 0.58 |
| ▸ | THRB | P10828 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13236587 | 1.00 | TUBB (0.75) | TUBBHSP90AA1TMPRSS4P2RX1HPGD | |
| SCHEMBL13812818 | 0.92 | TUBB (0.69) | TUBBHSP90AA1TMPRSS4P2RX1HPGD | |
| SCHEMBL23675446 | 0.91 | TUBB (0.72) | TUBBHSP90AA1TMPRSS4P2RX1HPGD | |
| SCHEMBL13812834 | 0.90 | TUBB (0.64) | TUBBHSP90AA1TMPRSS4P2RX1HPGD | |
| SCHEMBL23675443 | 0.90 | P2RX1 (0.64) | TUBBHSP90AA1TMPRSS4P2RX1HPGD | |
| SCHEMBL13812814 | 0.89 | TUBB (0.63) | TUBBHSP90AA1TMPRSS4P2RX1HPGD | |
| SCHEMBL3859317 | 0.88 | TUBB (0.65) | TUBBHSP90AA1TMPRSS4P2RX1HPGD | |
| SCHEMBL14741282 | 0.88 | HSP90AA1 (0.69) | TUBBHSP90AA1HPGDLMNAALDH1A1 | |
| SCHEMBL13812594 | 0.88 | TUBB (0.64) | TUBBHSP90AA1TMPRSS4P2RX1HPGD | |
| SCHEMBL4019571 | 0.87 | TUBB (0.63) | TUBBHSP90AA1TMPRSS4P2RX1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093401-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | The Board of Regents of the University of Texas System (US) | 2022-11-30 | — | — | EP | disclosed |