Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX1 | P51575 | 3/20 | 0.64 |
| ▸ | TMPRSS4 | Q9NRS4 | 2/20 | 0.64 |
| ▸ | TUBB | P07437 | 2/20 | 0.62 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.58 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.56 |
| ▸ | POLA1 | P09884 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30100461 | 0.90 | TUBB (0.75) | P2RX1TMPRSS4TUBBLMNAHPGD | |
| SCHEMBL13236587 | 0.90 | TUBB (0.75) | P2RX1TMPRSS4TUBBLMNAHPGD | |
| SCHEMBL13812847 | 0.89 | P2RX1 (0.58) | P2RX1TMPRSS4TUBBP2RX4P2RX7 | |
| SCHEMBL13812814 | 0.88 | TUBB (0.63) | P2RX1TMPRSS4TUBBLMNAHPGD | |
| SCHEMBL23675446 | 0.86 | TUBB (0.72) | P2RX1TMPRSS4TUBBP2RX4P2RX7 | |
| SCHEMBL13812668 | 0.86 | LMNA (0.80) | P2RX1TMPRSS4TUBBP2RX4P2RX7 | |
| SCHEMBL13812696 | 0.85 | P2RX1 (0.54) | P2RX1TMPRSS4TUBBLMNAHPGD | |
| SCHEMBL22074294 | 0.85 | P2RX1 (0.54) | P2RX1TMPRSS4TUBBP2RX4P2RX7 | |
| SCHEMBL13812615 | 0.85 | TUBB (0.59) | P2RX1TMPRSS4TUBBLMNAHPGD | |
| SCHEMBL26098397 | 0.83 | P2RX1 (0.64) | P2RX1TMPRSS4TUBBP2RX4P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIV OF TEXAS SY (US) | 2023-05-04 | — | — | US | disclosed |
| EP-4093401-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | The Board of Regents of the University of Texas System (US) | 2022-11-30 | — | — | EP | disclosed |
| WO-2021151104-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2021-07-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230140290-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | EIF2AK2, SARS1, ACE | P2RX1 3088/4885TMPRSS4 526/4885TUBB 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.