Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.44 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | SNCA | P37840 | 1/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2112731 | 0.88 | KMT2A (0.63) | KMT2AMEN1NPC1CA1CA2 | |
| SCHEMBL10949416 | 0.87 | NPSR1 (0.50) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| SCHEMBL407836 | 0.83 | L3MBTL1 (0.50) | KMT2AMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL874713 | 0.83 | KMT2A (0.61) | KMT2AMEN1NPC1CA1CA2 | |
| SCHEMBL31393776 | 0.83 | KMT2A (0.57) | KMT2AMEN1NPC1CA1CA2 | |
| SCHEMBL29273240 | 0.81 | KMT2A (0.62) | KMT2AMEN1NPC1ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8355067 | 0.81 | ADRA2C (0.49) | KMT2AMEN1NPC1ALDH1A1LMNA | |
| SCHEMBL2113091 | 0.81 | ESR1 (0.56) | KMT2AMEN1NPC1CA1CA2 | |
| SCHEMBL11379558 | 0.79 | TDP1 (0.46) | KMT2AMEN1NPC1CA1CA2 | |
| SCHEMBL10947407 | 0.79 | NPSR1 (0.42) | KMT2AMEN1NPC1ALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115403537-A | 2,3,5-trisubstituted-2,3-dihydro-oxatriazole derivative and preparation method thereof | 武汉工程大学 | 2022-11-29 | — | — | CN | disclosed |