Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | PARP1 | P09874 | 8/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | PTPN5 | P54829 | 3/20 | 0.41 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CDC7 | O00311 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4690983 | 0.93 | KDM4E (0.49) | KDM4EMAPTMEN1KMT2APARP1 | |
| SCHEMBL10780981 | 0.86 | KDM4E (0.44) | KDM4EMAPTMEN1KMT2APARP1 | |
| SCHEMBL307050 | 0.86 | KDM4E (0.53) | KDM4EMAPTMEN1KMT2APARP1 | |
| SCHEMBL290155 | 0.86 | KDM4E (0.45) | KDM4EMAPTMEN1KMT2AHTT | |
| SCHEMBL31270723 | 0.85 | KDM4E (0.53) | KDM4EMAPTMEN1KMT2APARP1 | |
| SCHEMBL1004217 | 0.85 | MEN1 (0.49) | KDM4EMAPTMEN1KMT2APARP1 | |
| SCHEMBL18222674 | 0.85 | KDM4E (0.53) | KDM4EMAPTMEN1KMT2APARP1 | |
| SCHEMBL300805 | 0.84 | ACMSD (0.50) | KDM4EMAPTMEN1KMT2APTGDR2 | |
| SCHEMBL9403931 | 0.84 | ACMSD (0.50) | KDM4EMAPTMEN1KMT2APTGDR2 | |
| SCHEMBL31011018 | 0.84 | ACMSD (0.50) | KDM4EMAPTMEN1KMT2APTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093401-A1 | SALICYLAMIDE DERIVATIVES AND RELATED METHODS OF MAKING | The Board of Regents of the University of Texas System (US) | 2022-11-30 | — | — | EP | disclosed |