Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 19/20 | 0.44 |
| ▸ | BRD4 | O60885 | 17/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26087076 | 1.00 | CREBBP (0.44) | CREBBPBRD4CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL26088574 | 0.83 | PIM2 (0.42) | CREBBPBRD4 | |
| SCHEMBL26086551 | 0.82 | BRD4 (0.39) | CREBBPBRD4 | |
| SCHEMBL30100774 | 0.82 | BRD4 (0.39) | CREBBPBRD4 | |
| SCHEMBL31329494 | 0.81 | MAP4K1 (0.51) | CYP19A1CYP2C9 | |
| SCHEMBL21646064 | 0.81 | MAP4K1 (0.51) | CYP19A1CYP2C9 | |
| SCHEMBL31329495 | 0.81 | MAP4K1 (0.51) | CYP19A1CYP2C9 | |
| SCHEMBL30100723 | 0.79 | HDAC3 (0.53) | CREBBPBRD4CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL26089027 | 0.79 | HDAC3 (0.53) | CREBBPBRD4CYP3A4CYP19A1CYP2C9 | |
| SCHEMBL26441332 | 0.78 | TRPV1 (0.45) | CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |