Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 6/20 | 0.39 |
| ▸ | CREBBP | Q92793 | 5/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.36 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26086551 | 1.00 | BRD4 (0.39) | BRD4CREBBPCRBNAAK1LMNA | |
| SCHEMBL31329494 | 0.82 | MAP4K1 (0.51) | CRBN | |
| SCHEMBL21646064 | 0.82 | MAP4K1 (0.51) | CRBN | |
| SCHEMBL31329495 | 0.82 | MAP4K1 (0.51) | CRBN | |
| SCHEMBL26087076 | 0.82 | CREBBP (0.44) | BRD4CREBBP | |
| SCHEMBL30100709 | 0.82 | CREBBP (0.44) | BRD4CREBBP | |
| SCHEMBL30100769 | 0.81 | BRD4 (0.57) | BRD4CRBN | |
| SCHEMBL26089057 | 0.81 | KDR (0.37) | BRD4CRBNLMNAL3MBTL1KDR | |
| SCHEMBL26441299 | 0.81 | BRD4 (0.57) | BRD4CRBN | |
| SCHEMBL26086646 | 0.80 | OTUD7B (0.38) | BRD4CRBNLMNAL3MBTL1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |