Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CASP3 | P42574 | 2/20 | 0.50 |
| ▸ | APAF1 | O14727 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.49 |
| ▸ | CMA1 | P23946 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 3/20 | 0.46 |
| ▸ | GSK3A | P49840 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23674985 | 1.00 | L3MBTL1 (0.52) | L3MBTL1MEN1KMT2ACASP3APAF1 | |
| SCHEMBL26086688 | 0.88 | L3MBTL1 (0.54) | L3MBTL1MEN1KMT2ACASP3APAF1 | |
| SCHEMBL5218062 | 0.87 | L3MBTL1 (0.49) | L3MBTL1MEN1KMT2ACASP3APAF1 | |
| SCHEMBL30100711 | 0.84 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ACASP3APAF1 | |
| SCHEMBL16163267 | 0.84 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ACASP3APAF1 | |
| SCHEMBL16163258 | 0.82 | L3MBTL1 (0.51) | L3MBTL1MEN1KMT2ACASP3APAF1 | |
| SCHEMBL14938439 | 0.77 | MEN1 (0.71) | L3MBTL1MEN1KMT2ACASP3APAF1 | |
| SCHEMBL17377477 | 0.76 | SCN9A (0.63) | L3MBTL1CASP3SCN9ACMA1GSK3B | |
| SCHEMBL30100689 | 0.76 | POLB (0.71) | L3MBTL1MEN1KMT2ACASP3APAF1 | |
| SCHEMBL30100692 | 0.76 | POLB (0.71) | L3MBTL1MEN1KMT2ACASP3APAF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093400-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | The Trustees of Princeton University (US) | 2022-11-30 | — | — | EP | disclosed |